类风湿性关节炎研究简报:Tofacitinib, Fish, Remission

保持最新的类风湿关节炎(RA)研究与我们的简要研究摘要。如果甲氨蝶呤(MTX)单独不能控制RA，添加口服Janus激酶(JAX)抑制剂Tofacitinib (Xeljanz)可能与添加生物制剂一样有效。JAX抑制剂属于第三类改善疾病的抗风湿药物(DMARDs)，称为靶向DMARDs。在一项对1146名类风湿性关节炎患者的研究中，这些患者对甲氨蝶呤单独治疗没有充分反应，大约三分之一的患者被转到tofacitinib，而其他人要么接受tofacitinib，要么接受生物阿达木单抗……more

Study Ranks Treatments for Knee OA

A new study takes a look at which approaches are best to bring relief to people with knee osteoarthritis (OA), a condition that affects approximately 20 percent of people over the age of 45 in the United States. Knee OA can be extremely painful and limit a person’s ability to function. Although there is no cure, numerous treatments are available to reduce symptoms, including over-the-counter and prescription drugs. Exercising and losing weight if a patient is overweight or obese also can help. Total knee replacement surgery is effective but is done only in cases where the disease is advanced and it’s ...more

Hyaluronic Acid for Osteoarthritis

If you have osteoarthritis (OA), you know all about joint pain and stiffness. One cause of these symptoms is the fact that hyaluronic acid (HA), a naturally occurring joint lubricant, breaks down in people with OA. To help alleviate the pain, your doctor might recommend treatment with hyaluronic acid injections – sometimes known as gel injections. What are HA injections? HA injections replace missing joint lubricant and are currently approved by the Food and Drug Administration (FDA) for use in the knees. However, some doctors may use the injections in shoulders and hips as well. The treatments will most likely take place in ...more

You Said It: PsA Skin Moisturizers

We asked our readers and followers “How do you keep your skin moisturized?” Here are their answers. I use Eucerin Intensive Repair Very Dry Skin Lotion and Eucerin in the jar. I also add oils like Pangea. — Suzanne McCue via Facebook I use Aveeno Eczema Therapy and argan oil after showers. — Claudia R. Hodak, Arundel, Maine I use CeraVe and humidifier with essential oils. — Donna Dixson, Atlanta, Georgia I use Cetaphil and sometimes Bag Balm for really cracked and inflamed spots. — Jodi Lynn Wilson Ruiz, El Paso, Texas For 30 years, I have only used Dove soap or Oil of Olay. In the past ...more

Rheumatoid Arthritis Flares: The Ups and Downs of Pregnancy

For some women with RA, pregnancy brings on an unexpected bonus: improved symptoms. Approximately 70% of women with RA experience improved symptoms in the second trimester that can last through the first 6 weeks after delivery, says J. Bruce Smith, MD, assistant compliance officer for research at Thomas Jefferson University in Philadelphia and a rheumatologist whose research has focused largely on autoimmune disease and pregnancy. There are several theories why disease symptoms improve, including increased anti-inflammatory cytokine levels and hormonal changes that occur during pregnancy. Exactly why some women with RA improve while others don’t is unknown, but a study out ...more

类风湿性关节炎研究简报:Remission, Biologics, Exercise

保持最新的类风湿关节炎(RA)研究与我们的简要研究摘要。吸烟、肥胖使风湿性关节炎难以控制根据最近的一项研究，超重或吸烟的风湿性关节炎患者更难得到缓解。美国和加拿大的研究人员收集了1100多名接受标准治疗的风湿性关节炎患者的数据，他们发现性别(女性)、超重和吸烟与早期症状严重程度没有显著关联。然而，随着时间的推移，所有这三个因素都会影响症状的改善程度。最显著的差异出现在那些超重或…more

Psoriatic Arthritis Research Briefs: Nail Changes, New Biologic, Biosimilar

Keep up-to-date on the latest psoriatic arthritis (PsA) research with our brief research summaries. Nail Changes May Indicate Psoriatic Arthritis Certain nail features can help doctors distinguish between psoriasis and psoriatic arthritis, and possibly lead to earlier or improved treatment for PsA, a new study suggests. In the analysis of 1,092 patients with either PsA or psoriasis only, researchers found that nail changes were more common among those with PsA than psoriasis only. Transverse (side-to-side) grooves, splinter hemorrhages (small broken blood vessels under the nails) and onycholysis (separation of the nail from the nail bed) were associated with arthritis. Transverse grooves were ...more

类风湿性关节炎研究简报:Remission, Surgery, Green Tea

保持最新的类风湿关节炎(RA)研究与我们的简要研究摘要。肥胖降低类风湿关节炎缓解几率研究表明，体重可能是类风湿关节炎患者能否达到疾病缓解的一个因素。一项研究综述筛查了3368例患者的病历。加拿大研究人员发现，与健康体重的患者相比，患有RA的肥胖患者获得缓解或维持缓解的可能性更低。他们报告说，在治疗期间，肥胖会对疾病活动和患者报告的结果产生负面影响。因此，他们说，应该调查降低BMI的干预措施是否有改善疾病结果的能力。来源:关节炎护理与研究，2017年1月more

You Said It: PsA Must-Have Item

We asked our readers and followers “What is your one must-have item for your psoriatic arthritis?” Here are their answers. Good, comfortable walking shoes with lots of support. — Patricia Flynn, Upland, California Good support network. — Garrett via Reddit A doctor that really listens and genuinely cares about my concerns with my care. — Kim Drouillard, Lincoln Park, Michigan I must have my electric jar opener. — Chrystal Tucker, Fayetteville, North Carolina My go-to copper compression gloves for the daily pain. Prayer for flares! — Kari Siemens, St. Louis, Missouri Pain medication when biologics and steroids are not working. — Anne Rowell, Houma, Louisiana A pool to exercise your joints weightlessly. — Kathy ...more

Are Women at Risk for Gout?

It was once thought that gout, the so-called “disease of kings,” typically spared queens. But in the last 20 years, cases of gout have more than doubled among women. Today, 2 million women – and 6 million men – in the U.S. have this inflammatory form of arthritis that causes joint swelling and telltale pain at the base of the big toe. Natural Gout Protection and Potential Triggers Gout occurs when high levels of uric acid build up in the blood and form needle-shaped crystals in the joints, causing pain, swelling and redness. Estrogen, a female hormone, protects women. It naturally causes ...more