几十年来用于治疗炎症性关节炎的两种药物也可能对一些手部骨关节炎(OA)患者有益。这是根据11月初在亚特兰大举行的2019年美国风湿病学会(ACR)年会上发表的两项新研究得出的结论。
Category Archives: Treatments
Best Approach to Managing Osteoarthritis
According to a study inArthritis Care & Research, people with hip and knee OA use oral pain medications far more than nondrug alternatives. Of the nearly 1,200 patients in the study, 70 to 82 percent took pain relievers; fewer than half triedphysical therapyor other nondrug options. Most were overweight, and none got the minimum 150 minutes of physical activity a week the Centers for Disease Control and Prevention recommends for good health.
That’s a problem, says Laith Jazrawi, MD, an orthopedic surgeon and chief of sports medicine at NYU Langone Medical Center in New York City. “We know that compared to people who are sedentary,patients who are more active have less painand better function.”
Disease-Modifying Drugs No Help for OA Pain
Disease-modifying antirheumatic drugs (DMARDs)根据一项新的荟萃分析，骨关节炎并不是手部或膝关节关节炎(OA)的有效治疗方法。The drugs are commonly used to treatrheumatoid arthritis (RA)and other forms ofinflammatory arthritis, but researchers in the United Kingdom (UK) found they were no better than placebo for OA pain. Their findings appeared in June 2018 inRheumatology.
DMARDs aren’t pain medications. They’re meant to slow the disease and prevent further damage to joints and organs by suppressing inflammation. When DMARDs work, pain usually improves as inflammation gets under control.
研究对膝骨性关节炎的治疗进行排名
A new study takes a look at which approaches are best to bring relief to people with kneeosteoarthritis (OA), a condition that affects approximately 20 percent of people over the age of 45 in the United States.
Knee OA can be extremely painful and limit a person’s ability to function. Although there is no cure, numerous treatments are available to reduce symptoms, including over-the-counter and prescription drugs. Exercising and losing weight if a patient is overweight or obese also can help. Total knee replacement surgery is effective but is done only in cases where the disease is advanced and it’s medically necessary.
So, which treatment is best? To help sort out the choices, a group of researchers set out to assess how the available non-surgical drug treatments stack up against each other for providing pain relief and improving physical function. The authors did not address lifestyle changes, likeweight lossandexercise. The study was published recently inJournal of American Academy of Orthopaedic Surgeons(JAAOS).
Hyaluronic Acid for Osteoarthritis
If you haveosteoarthritis (OA), you know all about joint pain and stiffness. One cause of these symptoms is the fact that hyaluronic acid (HA), a naturally occurring joint lubricant, breaks down in people with OA. To help alleviate the pain, your doctor might recommend treatment with hyaluronic acid injections – sometimes known as gel injections.
What are HA injections?
HA injections replace missing joint lubricant and are currently approved by the Food and Drug Administration (FDA) for use in the knees. However, some doctors may use the injections in shoulders and hips as well.
The treatments will most likely take place in your doctor’s office. The HA will be injected directly into the joint. The shots are usually given once a week for three to five weeks, depending on the brand used.
Anti-inflammatory Drug Doesn’t Help Hand OA
A new study found that hydroxychloroquine, adisease-modifying antirheumatic drug (DMARD)sometimes used to treatrheumatoid arthritis (RA)andlupus, does not reduce pain related toosteoarthritis (OA)手，可能结束了一个具有挑战性的问题的简单解决的希望。
Pain fromhand OAaffects an estimated 3 percent to 15 percent of adults over 60 and up to 31 percent of those over 70, making daily tasks difficult and diminishing quality of life. Increasing evidence suggests that low levels of inflammation may be an important source of pain in hand OA, at least in some people. Few medications are effective for hand OA other than traditional pain relievers, such asnonsteroidal anti-inflammatories (NSAIDs), acetaminophen and, in more intractable cases, opioids – all of which have side effects and can’t be used in certain populations. Researchers have been looking for other treatments.
Which OA Pain Reliever Works Best?
One of the benefits of modern medicine is the large selection of pain relievers available.The challenge is finding the right one at the right dose to reduce yourosteoarthritis (OA)pain. With so many available, which is the most effective?
A New Study Finds Pharmaceutical Chondroitin Helps Knee OA Pain and Function
Chondroitin sulfate improvesosteoarthritis (OA)knee pain and functional limitations in walking and daily activities as effectively as the anti-inflammatory drug celecoxib (Celebrex), according to a new study published recently inAnnals of the Rheumatic Diseases.But U.S. readers should know, there’s a catch: the researchers tested a version of chondroitin sulfate that is not available in this country.
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Study Confirms That Losing Weight May Save Your Knees
Losing excess weight may help preserve knee cartilage in people who have or are at risk of knee osteoarthritis (OA), according to researchers at the University of California, San Francisco (UCSF), whose findings were recently published online in the journalRadiology. Knee cartilage is the rubbery, slick cap that covers the ends of the upper (femur) and lower (tibia) leg bones that make up the knee joint.
他们的研究还发现，减掉多余的体重可以保护半月板，这是一种新月形的软骨垫，可以缓冲膝关节。Lead author Alexandra Gersing, MD, a postdoctoral scholar at UCSF School of Medicine, says this is especially important because atorn or damaged meniscuscan speed up the degeneration of the knee joint overall.
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New Pain Treatment for Knee Osteoarthritis Targets Nerves
A relatively new treatment for knee osteoarthritis (OA) appears to reduce pain better than traditional corticosteroid injections, according to a study published recently inInternational Journal of Rheumatic Diseases.
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