psoriatic psa treatment guideline

PsA Research Briefs: Comorbidities

Keep up-to-date on the latestpsoriatic arthritis (PsA)research with our brief research summaries.

PsA May Put Liver at Risk

People with PsA may have an increased risk of liver disease, according to a new study that followed more than a million people for an average of 6 years. People with psoriasis were 37% more likely to develop liver disease than those without inflammatory diseases, the study found. Those with PsA were 38% more likely to have liver disorders. Taking methotrexate further increased their risk.

SOURCE:Journal of Investigative Dermatology, April 2018

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psa research briefs comorbidities

PsA Research Briefs: Diabetes, Surgery, Fibromyalgia

Keep up-to-date on the latestpsoriatic arthritis (PsA) researchwith our brief research summaries.

PsA Increases Diabetes Risk

Having PsA may increase yourrisk of diabetes,根据最近的研究。加拿大研究人员对1978年1月至2014年11月间在一家大型专业诊所就诊的1305名PsA患者进行了研究,发现他们患糖尿病的风险比普通人群高出43%。PsA活性最高的人群患病风险最大,这表明炎症可能是这两种疾病的共同线索。

Source:The Journal of Rheumatology, published online February 2017

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psoriatic arthritis research brief

Psoriatic Arthritis Research Briefs: Nail Changes, New Biologic, Biosimilar

Keep up-to-date on the latestpsoriatic arthritis (PsA)research with our brief research summaries.

Nail Changes May Indicate Psoriatic Arthritis

Certain nail features can help doctors distinguish betweenpsoriasis and psoriatic arthritis一项新的研究表明,这可能会导致PsA的早期治疗或改善治疗。在对1092名PsA或银屑病患者的分析中,研究人员发现,PsA患者的指甲变化比银屑病患者更常见。横行(左右)沟、裂血性(指甲下小血管破裂)和甲骨松解(指甲与甲床分离)与关节炎相关。横沟与最靠近指甲的关节的关节炎和肌腱和韧带插入骨头的炎症显著相关。

Source: Journal of the American Academy of Dermatology, November 2017

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Psoriatic Arthritis Research Briefs: Disease Burden, Eye Surgery, New Biologic

Keep up-to-date onpsoriatic arthritis (PsA)research with our brief research summaries.

Enthesitis and Dactylitis Associated With Greater Disease Burden

The presence ofdactylitis– inflammation of the fingers and/or toes – and enthesitis – inflammation of the sites where the tendons or ligaments insert into the bone – can have important implications for people with PsA. A study of 1,567 PsA patients found that, overall, those with dactylitis or enthesitis had greater disease activity.

Additionally those with enthesitis had worse functional status, reported more pain and fatigue and were more likely to have work impairment. The study’s authors say their findings underscore the importance of identifying, assessing and managing enthesitis and dactylitis in people with PsA.

Source: Arthritis Care & Research, April 2017

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biologic psa

FDA OKs Biologic for Psoriatic Arthritis

The U.S. Food and Drug Administration (FDA) has approved the biologic drug abatacept (Orencia) to treatpsoriatic arthritis (PsA)在成人。It’s already approved forrheumatoid arthritis (RA)and for one subtype ofjuvenile idiopathic arthritis (JIA).

Abatacept is abiologic medicationthat works by targeting T-lymphocytes (T cells), immune cells that are overproduced in people with inflammatory arthritis. The drug, technically called a “selective costimulation modulator,” attaches to the surface of the cells, preventing them from communicating with other cells and producing chemicals that can lead to joint damage and symptoms like pain and swelling. It’s given as a monthly infusion or weekly injection.

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