Thanks to earlier diagnosis and more effective treatments, joint deformities in people withrheumatoid arthritis (RA)are becoming less frequent and severe.
What Causes Joint Deformities in RA?
Continue readingAggressive RA Treatment May Prevent Joint Deformities→
Early studies show an implanted device that sends electrical signals to the brain via the vagus nerve has potential as a new therapy forrheumatoid arthritis(RA).
Continue readingCan Nerve Stimulation Therapy Help Rheumatoid Arthritis?→
New research suggests that electrical impulses may one day be used to treatrheumatoid arthritis (RA).
Neurosurgeon Kevin J. Tracey, MD, president and CEO of the Feinstein Institute for Medical Research in Manhasset, N.Y., discovered that stimulating the vagus nerve, which extends from the brain stem to the stomach, could control the inflammation that is central to RA.
In healthy people, the nervous system, including the vagus nerve, maintains key bodily functions within a safe zone. One of the vagus nerve’s jobs is to control the production of tumor necrosis factor (TNF), a molecule that triggers inflammation. But in people with RA, the vagus nerve doesn’t keep TNF levels within the safe zone.
Continue readingFuture Rheumatoid Arthritis Therapy: Nerve Stimulation→
An emerging class of medications called janus kinase inhibitors (JAK inhibitors, orjakinibs) is offering new hope to patients withrheumatoid arthritis(RA) who don’t find relief with other treatments.
What are Jakinibs?
Jakinibs are a new class of medication, sometimes called oral biologics. The word “biologic” is misleading, however, because jakinibs work in an entirely different way than the biologics that have been used to date. Jakinibs are small molecules that workinsidecells. Traditional biologics such as etanercept (Enbrel), adalimumab (Humira), abatacept (Orencia) and Infliximab (Remicade) block pro-inflammatory cytokines fromoutside.
Jakinibs are taken by mouth. Traditional biologics are given through infusions or injections.
Continue readingWill Jakinibs Change Your Rheumatoid Arthritis Treatment?→