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eating fish rheumatoid arthritis

RA Research Briefs: Tofacitinib, Fish, Remission

Keep up-to-date on the latestrheumatoid arthritis (RA)research with our brief research summaries.

Tofacitinib Plus Methotrexate May Work As Well As Biologic

If methotrexate (MTX) alone fails to control RA, adding the oral Janus kinase (JAX) inhibitor tofacitinib (Xeljanz) may be as effective as the standard practice of adding a biologic. The JAX inhibitor belongs to the third category ofdisease-modifying antirheumatic drugs (DMARDs)called targeted DMARDs. In a study of 1,146 patients with rheumatoid arthritis that had not adequately responded to MTX alone, approximately a third were switched to tofacitinib, while the others received either tofacitinib or thebiologicadalimumab (Humira) along with methotrexate. At 6 months, only 38% of the patients receiving tofacitinib monotherapy achieved ACR50 – 50 percent improvement – while 46% of patients that received tofacitinib and MTX achieved that response. Forty-four percent of patients who combined adalimubab with MTX achieved the similar improved response of the tofacitnib and MTX group.

SOURCE:The Lancet, July 2017Continue readingRA Research Briefs: Tofacitinib, Fish, Remission

fish rheumatoid arthritis

Eating Fish May Relieve RA

Eating fish at least twice a week may help reduce inflammation and joint pain in people withrheumatoid arthritis (RA), according to a new analysis published recently inArthritis Care & Research.

Fish oil supplementshave long been known to improve pain as well as increase remission rates in RA patients takingtriple therapy. This is among the first studies to show that fish itself – withlower concentrations than supplements of the active ingredients, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) – may be just as good.

但是,该研究的作者表示,还需要进行更多的研究,并指出,“……我们无法就频繁食用鱼类对类风湿性关节炎活动的影响得出坚定的结论。”

Continue readingEating Fish May Relieve RA