Most of us know how sugar affects our waistline. Too much of the sweet stuff contributes to obesity, and with it, diseases like diabetes and heart disease. Overdoing it on one type of sugar in particular—the high fructose corn syrup found in sodas and processed foods—can also set off painfulgout. Considering that the average American eats 22 to 30 teaspoons of sugar daily, gout is yet another health risk worth noting.

Fructose is a natural sugar found in fruit and honey. High fructose corn syrup is a man-made sweetener produced from corn. It’s composed of 55 percent fructose and 45 percent glucose. Why is this type of sugar harder on your joints than other forms, like glucose? “Fructose is metabolized differently from glucose,” explains Peter Simkin, MD, emeritus professor of medicine in the University of Washington School of Medicine division of Rheumatology.

As the body breaks down fructose, chemical compounds called purines are released. The breakdown of purines produces uric acid—the substance that forms painful crystals in the joints and causes gout. Within minutes after you drink high fructose corn syrup-sweetened soda, your uric acid levels rise.Continue readingFructose and Gout: What’s the Link?→